Disodium hydrogen citrate syrup is a commonly prescribed drug that helps people with kidney stones, gout, and urinary tract discomfort by alkalizing urine. Preferred for its effectiveness and safety, disodium hydrogen citrate syrup comes in a variety of brands and strengths and can be used alone or in conjunction with other medications. It is still a crucial therapeutic option for the treatment of a number of renal and urinary diseases.
In This article, we will discuss about the disodium hydrogen citrate syrup uses, benefits, side effects, precautions, and more
What is Disodium Hydrogen Citrate Syrup?
Disodium hydrogen citrate, we also identifies as sodium acid citrate, which is a urinary alkalinizer. which makes the urine less acidic and promotes a mild diuresis. this syrup is metabolized after absorption to sodium bicarbonate.
Usually offered as a clear, colourless solution, it is preferred for its ability to raise urine pH and lower acidity, which relieves symptoms related to kidney stones, renal tubular acidosis, and some forms of UTIs. Its metabolized salts aid in balancing the excessive acidity of urine, facilitating patients’ removal of uric acid and other mineral deposits that could otherwise cause stones or worsen urinary discomfort.
Disodium Hydrogen Citrate Syrup Uses
Disodium hydrogen citrate is the main ingredient in this medicinal syrup. The source employed provides alleviation from renal tabular acidosis and kidney stones. Disodium hydrogen citrate has the following specific applications:
- Urinary tract infections (UTIs): By neutralizing acidic urine, disodium hydrogen citrate lessens burning and discomfort during urination.
- Kidney Stones: Disodium hydrogen citrate aids in the dissolution of some kidney stones and inhibits the formation of new ones.
- Gout: Disodium hydrogen citrate reduces the chance of crystal formation by lowering urine uric acid levels.
- Metabolic Acidosis: The body’s acid-base equilibrium is restored by disodium hydrogen citrate. Bicarbonate is metabolized by the syrup, which also raises the bicarbonate ions.
- Dysuria (painful urination): Disodium hydrogen citrate reduces discomfort brought on by urine that is too acidic.
- Alkalizer: By acting as an alkalizer, the syrup prevents acid from being present in the blood, urine, and stomach.
Disodium Hydrogen Citrate Syrup Treats In Kidney Stones
This Syrup aids in the treatment of kidney stones and renal tubular acidosis. The syrup acts as a preventative measure against kidney stone formation. It reduces the stones’ size, dissolves them in urine, and lessens the pain they cause. Calcium, phosphate, and other minerals found in the body can create kidney stones. When renal tabular acidosis occurs, kidney stones enlarge and cause unbearable pain because they are unable to dissolve in the body. This results in the presence of acid in the urine and blood.
The ingredients of this Syrup are added to the blood to maintain its pH levels and lower the concentration in the urine. It improves the solubility of cysteine and the ionization of uric acid by dissolving kidney stones and raising the alkalizer in urine.
As a result of the kidney stones being effectively dissolved, symptoms of kidney stone pain are improved, and the discomfort they cause is lessened.
Types of Disodium Hydrogen Citrate Syrup
The main form of disodium hydrogen citrate syrup is an oral liquid, usually in strengths of 1.37g or 1.4g per 5ml. To accommodate patient preferences, a number of brands produce this syrup with slightly different flavourings and excipients. Here are a few noteworthy varieties and brands:
- Alkadec Disodium Hydrogen Citrate
- Alkajan
- Elicitrol
Usually available in 100ml bottles, the strengths of Alkaroz, Aarklizer, Alkajas, Alkanov, Oricitral, and Cital Syrup range from 1.25g to 1.53g per 5ml.
Although the active ingredient in all of these formulations is the same, slight variations in flavour and concentration may affect tolerability for certain patients. There are also generic versions, which are frequently less expensive but have comparable effectiveness.
Disodium Hydrogen Citrate Syrup Combinations
To improve therapeutic results, some formulations include additional agents in addition to pure disodium hydrogen citrate syrup. Combining paracetamol or other analgesics with other medications to further reduce pain and inflammation associated with urinary disorders is a noteworthy example:
Disodium hydrogen citrate + paracetamol syrup: Urinary alkalization and a decrease in pain and inflammation during urination are two advantages of disodium hydrogen citrate + paracetamol syrup. These are mostly used to treat acutely painful urinary stone conditions.
Because of the higher risk of drug interactions and adverse effects, such combinations should only be used under medical supervision.
Dosage
Appropriate dosage is essential and customized according to patient characteristics and condition:
- Adults: Usually 15–30ml, diluted in water, twice or three times a day, after meals.
- Children: A pediatrician should determine the lower dosage. For example, according to medical advice, older children may receive 5–10 ml per day, while infants may receive 2 ml three times a day.
- Special Instructions: To reduce stomach discomfort and boost effectiveness, always take this medication after meals.Never take more medication than is advised without first consulting your doctor. Never take two doses at once; if you miss one, take it as soon as you remember.
Precautions
The secret to using any pharmaceutical medication successfully is to take the necessary precautions. In a similar vein, in order to achieve better results in life, you must adhere to some kind of advice when consuming sodium hydrogen citrate syrup. The safety measures you recommend are listed below.
- Take a small amount of the syrup or ask a healthcare provider for advice.
- In order to get the most out of this syrup, a person must stick to their diet and eat the products.
- Heart attacks, liver issues, kidney failures, and hypertension are among the medical conditions you must disclose to your doctor.
- Before consuming the syrup, you should properly inform your doctor about your health.
- Pregnant women and nursing mothers are suggested to refrain from consuming this syrup for the sake of both themselves and their unborn children.
- Do not treat the syrup like any other product because it is only intended for external use. It may result in serious adverse effects.
Side Effects
Disodium Hydrogen Citrate Syrup has multiple side effects such as:
- Pain in the abdomen
- Unsteady stools
- Feeling sleepy
- Vomiting and Nausea
- Headaches
- Muscle aches
- Changes in mood
- Fatigue
- Breathlessness
Medications to Avoid
Giving citrate salts and aluminium antacids at the same time is not recommended, especially for individuals who have renal insufficiency. Disodium hydrogen citrate should be used cautiously with anti-diabetic medications such as chlorpropamide, medications for bipolar disorder treatment such as lithium, anti-cancer medications such as methotrexate, antibiotics such as tetracyclines and methenamine, and medications for pain relief such as salicylates.
Disodium Hydrogen Citrate Syrup Pricing
| Brand Name | Strength (per 5ml) | Price (INR) |
| Alkanov | 1.37g | 108 |
| Brocit | 1.4g | 89 |
| Citalka | 1.4g | 111.3 |
| Oricitral | 1.4g | 75.5 |
| Alkajas | 1.37g | 75 |
| Elcitrol | 1.37g | 85 |
| Generic (Janaushadhi) | 1.4g | 20 |
Alternatives to Disodium Hydrogen Citrate Syrup
| Alternative Name | Main Ingredient | Indication | Price (INR, 100ml) |
| Citralka Syrup | Disodium hydrogen citrate | Kidney disease/stones | 111.3 |
| Oricitral Syrup | Disodium hydrogen citrate | Kidney disease/stones | 75.5 |
| Cital Syrup | Disodium hydrogen citrate | Kidney disease/stones | 85 |
| Polyalka Sodium Citric Acid Syrup | Sodium citrate | Urinary alkalization | 75 |
| Potassium Citrate Magnesium Pyridoxine | Potassium citrate & magnesium | Kidney stones | 170 |
| Generic (Janaushadhi) | Disodium hydrogen citrate | Urinary alkalization | 20 |
*Prices may vary locally
Conclusion
Because it can alkalize urine and prevent acid-related urinary tract issues, sodium hydrogen citrate syrup is a useful drug in the treatment of kidney stones, gout, and renal tubular acidosis. Given the possibility of drug interactions and contraindications, it is crucial to use this product under medical supervision. It comes in a variety of strengths and brands. Patients are required to closely follow dosage guidelines and keep an eye out for adverse effects.
Disclaimer
This article offers a broad summary solely for educational purposes. Disodium hydrogen citrate syrup should only be used after speaking with a licensed healthcare provider. Newer studies and market trends may cause changes to the information on dosages, costs, indications and side effects. Before beginning or altering a medication regimen, always double-check information and speak with registered pharmacists or health authorities.
Refresh Date: August 17, 2025
