Nise tablets are very widely recognized as non-steroidal and anti-inflammatory drugs (NSAIDs). They are used to manage pain, inflammation, and also fever. The Nise tablets contain an active ingredient called nimesulide, and these tablets are commonly also prescribed for patients who are suffering from arthritis, menstrual cramps, and post-operative pain.
This article will guide readers towards the composition, the benefits, side effects, precautions, and such of the Nise tablets, thus providing a detailed understanding of the medication.
What is the Nise Tablet?
Nise tablet is used to treat pain and symptoms of painful menstrual cramps. This is used to treat pain and other such issues.
The tablets are also consumed to treat dental pain, which might occur from damage to the tooth nerve, an infection, decay, or extraction or in most cases, an injury. These tablets contain nimesulide, which works by blocking out the effect of the prostaglandin chemicals.
The Nise tablets are, as we have mentioned, non-steroidal and they are diagnosed as NSAIDs.
Nise Tablets Composition
The tablets contain about 100 mg of nimesulide, although some variations like the Nise MDT (mouth dissolving tablets) and the Nise Kids (50 mg for paediatric use) also exist. These tablets might also include inactive ingredients like microcrystalline cellulose, magnesium stearate, and starch, which end up acting as binders or even stabilizers.
The exact composition of the inactive ingredients, however, may vary depending on the manufacturer, such as Dr. Reddy’s Laboratories Ltd, which is actually a key producer in India.
Nimesulide works by inhibiting cyclooxygenase (COX) enzymes, COX-2 in particular, which are known to be responsible for producing prostaglandins. If you are wondering what these are, they are the chemicals that send signals and trigger inflammation, pain, and fever.
By effectively blocking the production, Nise tablets provide quick relief from discomfort.
Nise Tablet Benefits
Every medication is taken to provide relief from pain, and Nise tablets are no exception to this. In fact, these tablets are quite versatile in their application, thus offering relief for a variety of conditions and issues such as:
- Pain Relief: It is known that the Nise tablets are quite effective in providing relief and comfort from mild to moderate pain, including from headaches, migraines, toothaches, muscle pain, nerve pain, and sore throat.
- Provides Anti-Inflammation Relief: Nise tablets are used mainly to manage inflammation in patients suffering from arthritis, osteoarthritis, and muscle injuries. By reducing such swelling and stiffness, the tablets help alleviate mobility and improve the quality of life for those who might have joint disorders.
- Relief from Fever Symptoms: Given that these tablets are used to relieve symptoms of pain, inflammation, and fever, it is noteworthy to mention that they have antipyretic properties, thus making them quite effective in lowering fever caused by common infections or other such issues.
- Comfort from Menstrual Pain: It is quite common to suffer from dysmenorrhea, which is basically menstrual pain, but with Nise tablets, you might be able to relieve your cramps and the discomfort along with it. There is a reduction from uterine contractions and also inflammation, thus providing significant relief from such symptoms.
- Relief from Post-Operative Pain: Interestingly, Nise tablets are also used to manage post-operative pain after undergoing surgical procedures.
- Dental Pain: In addition to already providing relief from these symptoms, Nise tablets also offer relief from symptoms caused by dental discomfort and pain in cases of infections, tooth decay, and even from dental procedures
Side Effects
While there have been slim to no cases of many side effects, it is quite important to keep the patient informed about the possible side effects that could occur. Here is a list of the possible but common side effects:
- Gastrointestinal Issues: This might be visible in the form of nausea, vomiting, diarrhea, stomach pain, heartburn, and even acidity. Taking medicine with food can help reduce these side effects.
- Dizziness and Drowsiness: Some patients might experience dizziness, weakness or sleepiness after having the medicine and this might cause inability to drive or operate heavy machinery, which is not recommended anyway.
- Skin Reactions and Allergies: Sometimes you might endure rashes, itching, and in some very rare cases, severe reactions like the Stevens-Johnson syndrome.
- Liver Abnormalities: Prolonged use or high dosage of the Nise tablets will ultimately lead to elevated liver enzymes – and in some extremely rare cases, severe liver damage.
- Other Side Effects: Another slightly uncommon side effect is increased heart rate, high blood pressure, or fluctuations and allergic reactions. In case these symptoms continue for a long period, it is recommended to consult a doctor immediately.
Dosage Directions
The dosage of the tablets is variable depending on the patient’s age, their condition,and medical history. However, here is a general guideline on the dosage as per age:
- Adults (18 years and above): The typical dosage for adults is 100 mg to 200 mg twice a day. This can be taken with or without food, but is considered to be taken after food to minimize gastrointestinal irritation.
- Adolescents (above 12 years old): For young adults, the dosage would be typically around 5 to 10 mg per kg of body weight per day. This can be divided into two or three doses as prescribed by a healthcare provider.
- Children (Below 12 years): Nise tablets are generally not recommended to such patients as this might increase the risk of liver damage. In some regions, the tablets are banned for paediatric use.
- Elderly Patients: Such individuals might require a lower dose of this tablet due to increased susceptibility to side effects, particularly those that are related to the kidney, liver, or any other gastro issues.
It is important to note that the tablets should be swallowed whole with a glass of water – they should not be crushed, chewed, or broken. It is recommended to take the medicine with food or milk, as this would reduce the risk of stomach upset.
In case you have missed the prescribed dosage, you can take it as soon as possible, but do not double the missed dosage to compensate, as this would lead to an overdose.
Nise Tablets Price
The price of the Nise tablets might be different depending on the region, manufacturer, and pack size. In India, a strip of 15 tablets of 100 mg would typically cost between INR 100 to 150 as of August 2025.
Online retailers like Pharmeasy offer the tablets at a discounted price of INR 103.09, whereas Apollo Pharmacy lists the same pricing. The Nise mouth dissolving tablets are sold at a price of INR 70.60.
Precautions
In order to ensure that the patient is using the tablets safely, the following precautions must be followed:
- Avoid Alcohol while being on medication, as this could lead to gastrointestinal bleeding and liver damage.
- In case you have medical conditions like liver disease, kidney disease, heart conditions, stomach ulcers, or bleeding disorders, then you might want to consult with your doctor before going ahead with this medication.
- Pregnant and Breastfeeding women are not usually prescribed such medications as this could cause potential risks to the foetus. This is especially true for mothers in their third trimester.
- Drug Interactions: Nise tablets may interact with medications like warfarin, methotrexate, furosemide, and suc,h thus increasing the risk of side effects. So it is important to inform your doctor about any medications that you might be taking.
- Allergies: It is not recommended to take Nise tablets if you are allergic to nimesulide or any other NSAIDs. It is important to seek immediate medical attention if you are experiencing signs of an allergic reaction.
- Storage: It is always recommended to store the tablets in a cool, dry place that is away from sunlight and away of the reach of children and pets.
Conclusion
Nise tablets offer an effective solution for managing pain, inflammation, and fever that is associated with conditions like arthritis, menstrual cramps, and post-operative recovery. Although they do offer a lot of benefits, the usage must be approached with absolute caution as the potential side effects, especially due to prolonged usage, may not be very well suited.
In fact, recent data from 2025 has also indicated that Nise tablets are still under scrutiny due to their liver toxicity, where prolonged periods, so it is always recommended to only have what you are prescribed.
Disclaimer
This article is only for educational purposes – it should not be used as a substitute for a doctor’s official prescription. Always consult your doctor before beginning a medication and also let them know about any past medications you have taken.
Refresh Date: August 29, 2025
