Clobetasol Propionate and Salicylic Acid is a conventional topical therapeutic drug used in the treatment of eczema, psoriasis and other conditions of the skin. Such skin disorders are commonly associated with itching, red and scalp spots of the skin that affect the level of comfort and quality of life. It is a combination of two potent medicines.
Liquid propionate lotion – a corticosteroid, which decreases redness, itching and swelling. Salicylic Acid: – a keratolytic (peeling) substance that dissolves coarse skin, eliminates scales and inhibits thickening. Collectively, clobetasol propionate and salicylic acid ointment are useful in dealing with skin conditions by regulating inflammation and skin regeneration.
What is Clobetasol Propionate and Salicylic Acid?
Clobetasol Propionate and Salicylic Acid is a topical steroid combined with woad acne treatment product. This is a topical product (applied to the skin) either in creams, ointments, or lotions. It is rubbed on patches of affected skin to help in drying the skin, as well as getting rid of inflammation, scaling and itching of the skin. It is a medicine doctors frequently prescribe to treat psoriasis, eczema and dermatitis, and resistant skin infections that do not respond well to less severe medication.
Clobetasol Propionate and Salicylic Acid Ointment Uses
| Condition | How it Helps |
| Psoriasis | Reduces skin cell overgrowth, removes scales, and controls redness. |
| Eczema | Relieves itching, swelling, and inflammation. |
| Contact Dermatitis | Reduces skin irritation caused by allergens or irritants. |
| Seborrheic Dermatitis | Controls flaking, scaling, and redness. |
| Resistant Skin Infections | Provides relief where milder medicines are ineffective. |
How Clobetasol Propionate and Salicylic Acid Works
This combination is made effective in two ways:
- lobetasol Propionate (Corticosteroid): Inhibits the release of inflammatory mediators such as prostaglandins that cause inflammation by increasing redness, itch and swelling.
- Salicylic Acid (Keratolytic): Helps to loosen thick skin, and also removes the dead cells. It is also a mild antibacterial, anti-inflammatory agent.
- This twofold effect makes the skin smoother, eliminates flare-ups, and makes it comfortable once again.
clobetasol propionate and salicylic acid Benefits
- Treats Redness and Swelling -Treats skin inflammation very well.
- Calms Itching – Gives instantest possible relief of repeated scratching.
- Banishes Scale and Rough Skin – Salicylic acid will smooth out the rough and scaly skin.
- Encourages skin healing- Enhances retention of moisture, and smoothness of skin.
- Treats Psoriasis and Eczema- Avoids flare-ups and decreases discomfort.
Clobetasol Propionate + Salicylic Acid Uses Instructions
In case of eczema, apply to affected skin once or twice daily with a thin layer of the cream/ointment/lotion.
- Apply with clean and dry hands or with cotton/gauze.
- Rub in softly on skin
- Avoid application of a bandage unless one is instructed.
- Not to be used on open wounds, blisters or burns.
- Wash hands immediately before and after use (except when used to treat hands).
Clobetasol Propionate + Salicylic Acid Storage Instructions
- Store in a cool, dry place away from sunshine.
- Keep away from the reach of children.
- Store below 25 degrees temperature .
Side Effects
Like all topical medicines, it may cause some mild side effects:
| Common Side Effects | Description |
| Itching | Mild irritation at the application site. |
| Dryness | Skin may feel slightly dry after application. |
| Burning Sensation | Temporary stinging or warmth. |
If symptoms persist or worsen, consult your doctor immediately.
Drug Warnings
External only
- Not advised to be used on diapers or on children under 12 years old.
- Avoid getting into prolonged use; prolonged use of the corticosteroid may thin the skin.
- Do not apply to sunburns, open sores, and chickenpox sores.
- Make sure to tell your physician about liver/kidney disease, diabetes, issues with blood circulation or Cushing syndrome.
- To pregnant women or women who are breastfeeding use only under medical supervision
- No naked flames should be used since clothes that are in contact with the ointment/lotion can burn easily.
Drug Interactions
| Type | Interaction |
| Drug-Drug | Inform your doctor about all dermatological medicines being used. |
| Drug-Food | No major interactions reported. |
| Drug-Disease | Use with caution if you have liver/kidney issues, Cushing’s disease, blood circulation problems, or severe infections. |
Safety Advice
| Category | Advice |
| Alcohol | Safe if prescribed; no known interactions. |
| Pregnancy | Use with caution; consult doctor before applying. |
| Breastfeeding | Consult doctor; avoid applying near breasts before feeding. |
| Driving | Safe; does not affect alertness. |
| Liver/Kidney Patients | Use with caution; doctor may adjust treatment. |
| Children | Not recommended below 12 years unless strictly prescribed. |
Habit Forming
Clobetasol Propionate and Salicylic Acid is not habit-forming.
Diet & Lifestyle Advice
- Use simple soap to wash with; do not use harsh chemicals.
- Wear loosely cotton clothes to minimise irritation.
- Wash socks and undergarments frequently.
- Never walk in barefeet in community shower areas or health clubs.
- Do not scratch or rub any affected parts
- Wash sheets, towels, and clothes frequently.
- Do not borrow personal things such as towels and combs
- Limit alcohol and caffeine which could induce a flare-up.
- Eat a well-balanced diet, manage stress, and drink fluids.
Special Advice
- Do not apply longer than 5 days in children (adrenal suppression risk).
- Within 5 days, when the symptoms worsen, see your doctor.
- Wash hands hygienically to prevent the transmission of infection.
Patients Concern – Disease Glossary
| Condition | Description |
| Eczema | Inflammatory skin condition with itchy, cracked patches often triggered by soaps, detergents, or stress. |
| Psoriasis | Autoimmune disorder causing red, scaly patches due to rapid skin cell growth. |
| Dermatitis | General term for skin irritation caused by allergies or irritants. |
Available Medicines for Clobetasol Propionate and Salicylic Acid
Here are some common brands and products available in the market:
| Medicine Name | Form | Pack Size | Price (Approx.) |
| Cambisalic Ointment | Ointment | 20 gm | ₹76.5 (MRP 85) |
| Cambisalic Lotion | Lotion | 1 Bottle | ₹162 (MRP 180) |
| Aktisalix Lotion | Lotion | 25 ml | ₹129.6 (MRP 144) |
| Csol-S Cream | Cream | 30 gm | ₹130.5 (MRP 145) |
| Csol-S Lotion | Lotion | 30 ml | ₹130.5 (MRP 145) |
| Cortent S Cream | Cream | 15 gm | ₹92.7 (MRP 103) |
| Cortirate-S Ointment | Ointment | 30 gm | ₹153 (MRP 170) |
| Clobilim-S Lotion | Lotion | 30 ml | ₹110.7 (MRP 123) |
| Clos-S 6% Ointment | Ointment | 30 gm | ₹112.5 (MRP 125) |
| Cloderv-S Ointment | Ointment | 20 gm | ₹81 (MRP 90) |
Prices may vary by pharmacy and location.
Conclusion
Lobetasol Propionate + Salicylic Acid dual action is a very powerful topical medicine to eczema, psoriasis and persistent skin irritations. Its bimodal effect of anti-inflammatory and descaling effects assists patients to have smooth and healthy skin. But, as it contains a powerful steroid, care should be taken in the use of it and it should be administered only under medical advice in children, in expecting women and stalwart users. Observing given dosage, safety guidelines, lifestyle parameters, and recommendations, patients may better cope with flare-ups and avoid their repeat occurrence.
Refresh Date: August 29, 2025
